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Did you know that AKG, alpha-ketoglutaric acid, a ketone derivative of glutaric acid, has been found to decline by 10-fold between the ages of 40-80? Yet, when it is replenished, it may help rewind your biological clock.*1 | | Did you know that AKG, alpha-ketoglutaric acid, a ketone derivative of glutaric acid, has been found to decline by 10-fold between the ages of 40-80? Yet, when it is replenished, it may help rewind your biological clock.*1 |
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How does AKG support healthy aging?*
It may help facilitate our internal cellular recycling process known as autophagy.* Autophagy is a critical component of cellular rejuvenation through which the body recycles old cellular components and promotes cellular renewal.
Researchers have discovered a link between autophagy and longevity. They learned that increases in autophagy activity correlated with increases in not only lifespan but also healthspan. Conversely, compromised autophagy was recently recognized in 2023 as one of the 12 hallmarks of aging.*
| | AKG may also support longevity through activating AMP-activated protein kinase (AMPK) — a pathway that helps maintain cellular energy balance by supporting the function of our cells’ main energy hubs, the mitochondria.*2,3 | | The ProHealth Advantage
We offer AKG with a calcium salt attached to the molecule; this slows the absorption of AKG for optimal protein synthesis and ATP production. It also further supports the metabolism of all essential amino acids and can assist in the reduction of ammonia levels in the body.*4
| | References
1 - Demidenko O., et al. Aging. 2021;13(22):24485-24499.
2 - Garcia D., et al. Molecular Cell. 2017; 66(6), 789–800.
3 - Bareja A., et al. Frontiers of Cell and Developmental Biology. 2019; 7:183.
4 - Maria M., et al. Ageing Research Reviews. 2021; 101237. | | | | |
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. | | | | |
