Zone Diet - October 2, 2025

What Really Causes Obesity?

How AMPK Activation Can Help Prevent

Long COVID-19

It’s been nearly five years since COVID-19 first appeared, but for many, the effects of infection still linger.

Long COVID now affects millions worldwide, with more than 200 different symptoms tied to it. Research shows that a big part of the problem comes down to AMPK, the body's master switch for metabolism. When AMPK activity drops, it sets the stage for increased inflammation.

In this week’s article, I’ll explain how keeping AMPK continually activated through Metabolic Engineering® may not only lower the risk of long COVID but also help your body stay resilient against future COVID variants.

Read More at DrSears.com

Pair Apple Cinnamon ZoneRx Oatmeal and ZoneRx Granola for the easiest, most delicious way to hit your morning protein goals.
Each serving delivers 15g of protein, 6–7g of fiber, 0g added sugar, and just 190–220 calories.
Helps stabilize blood sugar, control hunger, and activate AMPK for optimal metabolic health.

Shop Oatmeal at ZoneLiving.com

Shop Granola at ZoneLiving.com

What Really Causes Obesity?

Obesity rates continue to climb, but the real question is why. Is it due to lack of exercise, or are we simply overeating? The science says the answer isn’t what most people expect. While exercise plays a role, it's a small one. The real driver lies in the way our metabolism functions.

In this week’s “Ask Dr. Sears,” I’ll break down what really causes obesity, why popular weight-loss drugs may be doing more harm than good, and how the Zone Diet offers a smarter, science-based solution to lose fat while protecting lean body mass.

Read More at DrSears.com

Inside The Unforgettable Zone Conference in Argentina

I was honored to travel to Rosario, Argentina last month as the featured speaker at the Congreso Internacional en el Uso de la Ingeniería Metabólica.

It was inspiring to share how Metabolic Engineering® and living in the Zone can transform lives—especially alongside such passionate communities.

A heartfelt thank you to Zone Argentina, Zone Uruguay, and Zone Paraguay for helping bring together another unforgettable event. To give you a sense of the energy in the room, they’ve put together a short and cinematic video recap of the highlights. Click on the thumbnail to see it!

https://www.youtube.com/channel/UCc1LeMY1lILwAN9D_3vrDDA

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Disclaimer: The entire contents of this website are based upon the opinions of Dr. Barry Sears, unless otherwise noted. Individual articles are based upon the opinions of the respective author, who retains copyright as marked. The information on this website is not intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. It is intended as a sharing of knowledge and information from the research and experience of Dr. Sears and his Zone community. Dr. Sears encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional.